So Effective because we use the finest natural ingredients

Cherry Juice

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RED CHERRIES: Anti inflammatory, anti-carcinogenic, a natural source of melatonin which  helps regulate sleep cycles, CHERRIES are a good source of anti-aging anti-oxidant properties, helps reduce muscle pain, regulates blood sugar, lowers blood pressure.

Ceylon Cinnamon

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*CEYLON CINNAMON OIL  -- (the good cinnamon) contains polyphenols and has anti-inflammatory properties. It can help regulate blood sugar,  is anti-fungal agent that fights both viral and bacterial infections and can fight against brain degeneration

Pineapple Juice

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PINEAPPLE JUICE: Studies show it may contribute to cataract prevention, asthma prevention, and may help boost fertility, it may help fight cancer and heart disease, reduces bloating, helps ulcerative colitis, fights free radicals, and is a source of bromelian which helps osteoarthritis

Juiced Ginger

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*GINGER -- an-anti-nausea, anti-inflammatory agent. Considered an immune-system booster, helps with digestive issue and is good for the skin GINGER also  reduces nausea, muscle pain, inflammation (relieves some joint pain and osteoarthritis), Lowers blood sugar, reduces menstrual pain, lowers cholesterol, may improve cognitive function, fights bacterial infection.

Organic Hibiscus Blossom

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HIBISCUS:  Relieves menstrual cramps, improves digestion, lowers cholesterol, protects the liver, aids in weight loss, is an antidepressant, anti-inflammatory. Can stimulate menstruation in large dosages. In infusions, the topmost concentrations of Anti-Oxidants & Al, B, Cu, Fe, P, K, Mn, Ni, Zn It seems to be possibly one of the top contributors of B from food (up to 5.5±0.2 mg/L). The Mg contained in the infusion (up to 106±5 mg/L) A high amount of accessible Mn (up to 17.4±1.1 mg/L) In short, hibiscus tea was the tea that provided the most anti-oxidant properties.

Herbs

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Moringa: Loaded with anti-oxidants, reduces cholesterol & inflammation


GUAVA LEAF: Full of antioxidants, flavonoids quercetin, anti-inflammatory agents, antibacterials, and tannins that can help treating stomach troubles and aid in chronic diseases. Scientific studies have documented guava leaf helping with diarrhea, preventing fluctuation in blood sugar levels, reduction in cholesterol, improves cognitive function and promotes relaxation. (Guava leaves may also help with hair loss)Ground Hemp Seeds, 



HEMP: The ground seeds (which are present in small amounts, in several versions of this tea) contain all the amino acids to make it a complete source of plant-based protein -- rich in Omega 3’s and vitamin K, antioxidants. This helps reduce blood pressure.


Ground Green Matcha & Sencha Tea are loaded with anti-oxidants,  a metabolism booster and a source of cancer-fighting agents like L-theanine. GROUND GREEN TEA Provides slow-release caffeine, boosts memory and concentration. Fortifies immune system, promotes skin health and endurance.

Anti-Inflammatory Agents

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Hibiscus. Turmeric, Milk thistle. Tamarind, Love for your liver!

 MILK THISTLE: Good to take with statins, protects the liver, is a neuro-protective that reduces amyloid plaque, which can assist Parkinsons and Alzhiemers, stimulates bone mineralization, can lower blood sugar levels, increase breast milk production, assists in gallbladder function and may protect from some types of mushroom poisoning


TURMERIC: Anti-inflammatory, neutralizes free radicals, increases brain-derived neurotropic factor, which reduces depression (test subjects showed improvement and results similar to prozac), improves memory and may even protect against Alzheimers, reduces heart disease, inhibited the growth of cancerous cell in laboratory animals, helps ease arthritis pain


TAMARIND: The well-studied benefits include its ability to reduce inflammation throughout the body, improve vision, boost respiratory health, heal skin conditions, and improve the digestive system. Tamarind also relieves pain, boosts the immune system, reduces fever, lowers cholesterol to improve the cardiovascular health, treats piles, may help prevent cancer, supports liver functions and protects against parasites and worms.


Organic Honey/Manuka Honey

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*ORGANIC  HONEY --A good source of antioxidants called phenolic compounds. It has antibacterial and antifungal properties. It is filled with Phytonutrients and is known to soothe a sore throat. Organic honey is rich in anti-oxidants, lowers cholesterol and blood sugar, cough suppressant, promotes healing. Sweet and soothing.

Organic Manuka Honey, which we import from New Zealand has one of the highest anti-microbial and anti-biotic properties known to man, and it does not cause anti-biotic resistance.

Lemon Juice

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*LEMON JUICE-- It is loaded with vitamin C, which the body can't store and must be replenished daily. LEMON JUICE also reduces calcification, kidney stones, promotes heart health, helps with absorption of minerals, fights disease. Some tests indicate that it may create an alkaline environment in the body, which is believed to inhibit cancer growth, although the tests have not proven conclusively that this is the case.

Cayenne

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CAYENNE: Boosts Metabolism, lowers blood pressure, reduces muscle pain

Elderberries

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* ELDERBERRIES: One of the best sources of polyphenols. High in anti-oxidants. An anti-inflammatory agent. Studies have shown polyphenols can help reverse artery damage, reduce the risk of cancer and gum disease and speed up recovery time when fighting a cold or flu. ELDERBERRIES are an anti-viral, anti-inflammatory agent, Scientifically proven to speed recovery from colds and flu — 90% of the elderberry test group were completely well again within 2 – 3 days compared to 6 days in the placebo group. See link to study below) Travelers who used elderberry for 10 days before travel and up to 5 days after arriving overseas experienced an average 2 day shorter duration of their colds, and a noticeable reduction in their symptoms. Extremely effective for runny noses and congestion. Anti-catarrhal herbs prevent excess mucous formation and aid in removing mucous and reducing inflammation in the body.  Helps with UTI’s  Increases nutrient uptake, reduces gas. Used  in ancient Egypt and Native American remedies for thousands of years.



CBD's have  been shown to reduce seizures, provide relief from anxiety and depression and muscular pain..  This is excerpted rom a New York Times Article:  “I’m a 30 y.o. male who has not experienced a single anxiety free day in my adult life,” wrote one user on a CBD forum on Reddit earlier this month. “About 3 weeks ago I started taking CBD- and I can’t even describe how amazing I feel. For the first time in 15+ years I feel happy and look forward to living a long life.”“CBD is the most promising drug that has come out for neuropsychiatric diseases in the last 50 years,” said Dr. Esther Blessing, an assistant professor at New York University School of Medicine, who is coordinating a study of CBD as a treatment for post-traumatic stress disorder and alcohol use disorder. “The reason it is so promising is that it has a unique combination of safety and effectiveness across of very broad range of conditions.”

The National Institutes of Health database lists about 150 of studies involving CBD as a treatment for conditions as varied as infantile spasms and Parkinson’s disease.


And the research has led to medical treatments. In June, the Food and Drug Administration approved a cannabidiol-based drug called Epidiolex as a treatment for severe forms of epilepsy, representing the first government-sanctioned medical use for CBD.


Preliminary research also indicates that CBD may be effective as an antipsychotic in reducing the symptoms of schizophrenia, with fewer side effects compared with current antipsychotic drugs, Dr. Blessing said.


Real VANILLA: Anti-oxidant, anti-inflammatory, mood elevator, anti-bacterial agent, fever reducer, lowers cholesterol


Magnesium Glycinate: Magnesium is called the “Miracle Mineral” because it is involved in practically every body function.  Unfortunately, it’s also one of the most common nutrient deficiencies today; It is estimated up to 80% of adults are deficient in magnesium because stress, alcohol, processed foods, antibiotics and other common medications quickly deplete this critical mineral, which is why our Wild Child Revitalizing Elixir is a great source of Magnesium Glycinate.


D-3/K-2


SELENIUM


B-COMPLEX (INCLUDING THIAMINE)  Thiamine deficiency is common among those who consume alcohol, and it can lead to depression and an assortment of ailments.

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FEATURED INGREDIENT OF THE MONTH:

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MORINGA


7 Health Benefits You Must Know About Moringa Oleifera!



Moringa is rich in antioxidants and nutrients. Its powerful health benefits include the ability to protect the liver, fight inflammation, and lower cholesterol. Moringa extract and powder can help give relief from stomach disorders, allergies, and edema.


1. Powerful Antioxidants

The moringa plant offers a rich blend of powerful antioxidants such as kaempferol, caffeoylquinic acid, zeatin, quercetin, rutin, chlorogenic acid, and beta-sitosterol. These powerful antioxidants found in moringa possess free radical scavenging capacity and have shown its therapeutic value in curing the damage caused by oxidative stress.

2. Boosts Immunity

The ethanolic extracts of moringa leaf help in stimulating the immune system of the body. It also helps in enhancing the cellular immune response and exerts positive effects on various other immune system values such as total leucocyte count, antibodies, and hypersensitivity reaction.

3. Balances Blood Sugar

High blood sugar is on the rise—and it comes with a raised risk of diabetes and heart disease. Enter Moringa. Several studies have demonstrated that Moringa may help lower blood sugar, and as a result, reduce the risk of diabetes. The same study that looked at postmenopausal women also found a 13.5% reduction in fasting blood glucose. Another study on animals found that an oral dose of Moringa reduced fasting blood glucose by 26.7%. Moringa, combined with a healthy diet low in processed sugars, could be very beneficial in helping to treat and prevent diabetes.

4. Reduces Cholesterol

Moringa is effective in maintaining optimal levels of blood pressure and cholesterol levels in the body. Bioactive components such as isothiocyanate and niaziminin present in it prevent the thickening of arteries and reduce the development of pulmonary hypertension. Studies have confirmed its hypocholesterolemic effects help in reducing a high-fat rise in the liver, kidney, and serum cholesterol levels.

5. Improves Digestion

If bloating, gas, and bathrooms woes seem to always have you down, Moringa might offer a natural solution. Thanks to its high antioxidant content, Moringa might also be a good tool to improve your digestion, and better manage digestive disorders, according to some studies. A 2014 study found that Moringa’s anti-inflammatory properties had a beneficial effect on colitis. Compared to controls, Moringa was able to reduce the severity of ulcers and overall inflammation. This promising research shows that Moringa might be a great natural option for people with IBD conditions looking to prevent recurrences.

6. Reduces Inflammation

Speaking of inflammation in the brain, Moringa actually reduces inflammation in the whole body. Inflammation is linked to almost every chronic disease: dementia, heart disease, cancer, diabetes, obesity, the list goes on. Moringa suppresses inflammatory enzymes, and one study found that the bioactive compounds in Moringa, specifically from consuming a pod extract, may help with the prevention of chronic illness. Another study showed that Moringa was able to decrease gene expression and the production of inflammatory markers, which helped to alleviate low-grade inflammation in the body.

7. Improves And Rejuvenates Skin

Not surprisingly, Moringa has natural anti-bacterial and anti-microbial properties. This combined with its high antioxidants and anti-inflammatory abilities make it great for improving and protecting the skin. One study found that Moringa was able to enhance skin revitalization, giving it anti-aging properties, and it can also help with everything from wounds, burns, acne, and dandruff.

CBD and MS

Additional Information

CBD has been helpful for those suffering from Multiple Sclerosis (MS) which is an autoimmune disease characterized by chronic inflammation of the myelin sheath that encloses nerves in the brain and spinal column. When this tissue becomes inflamed for long periods of time, it causes irreversible tissue damage that inhibits the ability of the nerves to communicate with the body through the central nervous system. The result of this damage is chronic pain, loss of motor control, fatigue, and muscle spasticity and weakness. Over the last several years, extensive research has been performed to study the effects of cannabioids on the symptoms associated with MS. The results have been astounding. Cannabinoids found in the compounds including psychoactive THC (which we do not put in our products at this time) and non-psychoactive CBD have proven to reconstruct the natural process our body performs through naturally occurring endocannabinoids. In autoimmune patients such as those with MS, the body does not adequately produce these endocannabinoids due to the immune system attacking the DNA of the individual. This attack causes a breakdown in normal body processes, resulting in a nervous system that cannot function properly. The compounds found in cannabis connect to the cannabinoid receptors and pain receptors in the body and act as a stand-in to promote this healing process. The results are remarkable and lead to a much better quality of life for those suffering from this disease. Here's a closer look at how CBD can help: Reduces Muscle Spasticity THC and CBD are proven to dramatically reduce uncontrollable muscle spasms including the spasms that cause the frequent urge to urinate. Israel’s Tel Aviv University conducted a research study in which they infected mice with the condition that mimics MS. When they injected the mice with CBD, the mice were able to walk again. Before the CBD, the legs of the infected mice were crippled by stiffness and tightness. The mice treated with CBD also showed a significant decrease in nerve damage and overall inflammation. Another study performed at The University of Plymouth in 2012 found cannabis to be twice as effective at providing relief of muscle pain and spasms than a placebo. After 12 weeks of using cannabis, patients reported a much higher reduction in spasticity than those who received a placebo. Eases Nerve Pain: Cannabis helps ease a lot of the nerve pain associated with MS. Cannabinoids are a powerful analgesic that engages pain receptors in the body, significantly reducing chronic pain. This chronic pain is caused by inflammation of nerve tissue, which leads to pain signals being sent throughout the body. Just as having something pressing on a nerve in one’s back can cause pain to travel down their leg, often, a patient will feel a large amount of pain in an unaffected area of the body due to damaged nerves signals traveling to the area. By reducing the inflammation on the nerves, patients find much-needed relief from this pain. Reduces Inflammation The common thread to the majority of symptoms of MS is the effect chronic inflammation has on the body. This inflammation is the number one culprit of much of what ails MS patients. Cannabinoids found in cannabis are very potent anti-inflammatories. THC and CBD compounds derived from cannabis deactivate this immune response that leads to chronic inflammation and stops the attack on the central nervous system. The compounds are also powerful antioxidants which contain neuroprotective properties. This capability protects the cells, tissues, and DNA from damage. When unprotected, the tissues become inflamed and irritated which leads to deterioration. This decline sends pain signals through the nerves throughout the body leading to intense pain. The cannabinoids found in these compounds helps prevent this and promote neurogenesis, or the creation of new brain cells. Aids Digestion MS patients commonly have severe gastrointestinal issues like constipation, uncontrolled bowels, and difficulty with digestion. Cannabis can help with all sorts of issues in the body at the same time. 70% of immune cells are found in the gut, and cannabinoids engage these immune cells and quiet the inflammation in the bowels. Certain cannabis varieties act as an appetite stimulant, helping those who have difficulty maintaining a healthy weight due to digestion issues. Cannabinoids trigger the release of natural hunger hormones which in turn triggers a healthy metabolism. Cannabis writer Anna Wilcox compares this process to a traffic police officer: They direct the flow of hormones and chemicals that communicate with the body’s systems like a traffic cop to keep chemicals and hormones flowing properly. CBD also Acts as a Sleep Aid.  Most MS patients have difficulties sleeping. Uncontrollable pain and spasticity in the muscles make it tough for individuals to fall asleep and stay asleep through the night. Cannabinoid strains high in the terpene myrcene and the cannabinoid CBN)put the body to rest allowing patients to fall asleep faster, sleep through the night, and to achieve extended periods of deep sleep. This is especially important as the body repairs itself, rebuilds bones, and repairs the immune system during this phase of sleep. A GW Pharma study in 2000 showed patients who used cannabinoids experienced less pain and reported better sleeping patterns than those who did not. Improves Vision: You have cannabinoid receptors throughout your entire body, skin, connective tissues, organs, brain, and the eyes. Many MS patients experience blurred vision or the complete loss of vision. This issue is a result of inflammation of the optic nerve. The anti-inflammatory properties of cannabis reduce this inflammation, leading to clearer vision. This property is the same principle used in treating patients with glaucoma and retinal degeneration with cannabis. Alleviates Depression : One of the most troublesome symptoms for MS patients is chronic depression. The ongoing pain and debilitating effects MS has on the body leads to a low quality of life for many people, leading them into a deep depression. This is also caused by the inability of the body to produce naturally occurring endocannabinoids in the brain. Introducing the cannabinoids THC and CBD to the system compensates for this, lifting spirits and reducing the painful effects of MS that lead to depression. Researchers have learned a lot about MS through their research involving cannabis. It has helped them to understand how our body communicates and the role endocannabinoids play in keeping our body’s systems communicating properly with one another. When there is a breakdown in communication in one area, it has a domino effect on the rest of the systems of the body. By inserting these missing pieces to the puzzle, we slow down the autoimmune reaction, stop inflammation, improve muscular control, and reduce or eliminate the side effects of MS

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Site Content

Additional Information

August 31, 2017

Elder For Influenza

Justin Cooke  Herbs, virology

Viral infection poses a significant risk to public health across the world. 


Elder offers a unique mechanism of stopping the influenza infection. 


In the past 100 years there have been four significant outbreaks of influenza, one of which wiped out nearly 6% of the worlds entire population, making it arguably the most catastrophic events in human history.


The problem with influenza is that it mutates rapidly, allowing it to change and adapt to different environments. Through this mutation and adaptation, influenza is able to develop resistance to the most common drugs used to treat it. 


Eventually, in much the same way as drug resistant bacteria, the infection will no longer be treatable. 


Thus increasing the severity of the disease significantly. 


Plant medicine offers some support with slowing or preventing resistance to treatment. 


There are often many chemicals in plants that provide similar effects, or ameliorate the mechanisms of resistance (for example). 


In the case of influenza, having multiple inhibitory effects on different stages of the infection process can both reduce the chances of resistance, and increase efficacy.

elderberry extract.jpeg

 How Pharmaceutical Medications Treat Influenza

There are 3 main anti-influenza medications on the market, which I have written about in more detail in my recent article on Drug Therapies For Influenza. 


Modern drugs include Zanamivir, Oseltamivir, and Peramivir. 


These medications mainly work off a viral protein known as neuraminidase, which is essential for allowing newly formed viruses to exit our cells to infect new host cells. 


In recent years, however, there have been increased reports of resistance to these medications. 


Older anti-influenza medications work off a special ion channel contained in the viral envelope of influenza A (not B or C). 


By inhibiting this ion channel, the virus cannot infect the nucleus of the cell to create new copies of itself, thus inhibiting the infection. 


Unfortunately drug resistant strains of influenza are so common to these medications they are no longer reliable, and not commonly used. 


The problem with these medications is that because there is only one chemical involved, with one mechanism, it's easy for a virus to develop resistance. 

drugs for influenza

 


What Is Elder?

Elder, (Sambucus spp.) is a common shrub or tree species found around the world. 


The berries, bark, and leaves are used in traditional medical systems for upper respiratory tract infections, and a few other conditions not related to infection. 


The use of elder dates back a very long time. 


Evidence of elder seeds, pollen, and dried fruits have been found at a Bronze Age archaeological site in Tuscany (Italy) [2], a Neolithic site in the French Alps [3], and a Durankulak site on the Black Sea coast and north-eastern Bulgaria [3]. 


In recent years, elder has seen a surge in popularity after a series of case studies suggested its efficacy for influenza. 


Since then, there’s been an increase in scientific research on the plant to identify the mechanisms, in the hopes of developing new drugs to treat drug resistant strains of influenza. 


Studying the plant is difficult, since the phytochemical profile of the plant is so complex. Finding the mechanisms of action for a plant with as much as 100 active ingredients is incredibly challenging. 

elderflower.jpg

 


How Does Elder Fight Viral Infection?

In a recent article discussing the mechanisms behind how the influenza virus infects our cells, I highlighted the main steps needed for influenza to enter and infect our cells. 


This is important to understand when talking about treatment mechanisms for the virus so if you are not familiar with how influenza works I suggest you start at this article. 


 


1. Neuraminidase:

As mentioned, the main mechanism of action for pharmaceutical drug therapies for influenza is to inhibit neuraminidase. 


By doing to the virus can replicate, but can't leave the cell and infect new hosts. 


This effectively inhibits the infection, but will only work in the early stages of the infection before it has infected too many hosts. 


Some of the phytochemicals in elder work off this same mechanism, inhibiting the neuraminidase protein complexes on the viral envelope. 


These chemicals include the flavonal glycosides, and special lignans known as RIPs (ribosomal inactivating proteins).


 


2. Hemaglutinin:

These same chemicals are thought to bind to, and inhibit the hemagluttinin spikes of the virus as well, which it needs to enter the cells. 


We can test for this through something known as a hemagglutination inhibition (HI) assay which looks for the amount of hamaglutinated blood cells after exposure to different phytochemical extracts of elder. 


The lignan content of elder has been shown to inhibit hemagglutination in vitro [1]. 


Inhibition of hemagglutinin is one of the main mechanisms of natural antibody mediated immunity, and is considered to be the best mechanism for the treatment of influenza. 


There’s been some effort in recent years to develop drugs that work off this mechanism (rather than neuraminidase), but the complexity of the hemagglutinin molecule, and the variability of it within the influenza family (there are 16 different types), makes drug discovery both time consuming, and incredibly expensive. 


We have not yet been successful in developing a drug that has the same ability as the ligans are thought to provide from plants like elder or phytolacca.


These ligands are also considered to be the source of the toxicity of elder, more specifically the type 1 RIPs which are resistant to breakdown in the stomach by pepsin. 


Heat treating elder preparations makes them succeptible to pepsin, which significantly reduces toxicity. 


Elder is considered a safe and effective treatment, with the main side effect being nausea and vomiting. 


These symptoms can be avoided by reducing the dose at the onset of symptoms, and through heat treatment of all elder preparations. 


 


3. M2 Ions

Thirdly, some of the phytochemistry of elder, namely the flavonol glycosides and anthocyanidins have been suggested to inhibit the M2 proteins located on the viral envelopes of influenza A. 


This is the mechanism of action for the older generation of anti-influenza drugs like amantadine hydrochloride. 

influenza-A-diagram.jpg

Sambucus nigra/canadensis

Mechanism Of Action:

Hemaglutination inhibitor

Neuraminidase inhibitor

May provide M2 ion channel inhibition

Pharmacokinetics:

The majority of constituents are absorbed well orally

Some of the constituents may be conjugated through CYP3A4 enzymes.

Excreted in the urine and feces

Pharmacodynamics:

Viral membrane binding has been shown, but the bioactive constituents for hemagglutination inhibition, m2 ion inhibition, or neuraminidase inhibition has not been confirmed.

Pregnancy:

Likely Unsafe. Not recommended.

Interactions:

My interact with herbs or drugs affecting the CYP3A4 pathway.

Adverse Reactions:

Nausea and vomiting.

Contraindications:

Do not use fresh berries, or untreated stems, leaves, or bark the heating process eliminates much of the emetic potential of the plant.

Strengths:

Multiple, direct antiviral actions, including the preferred hemaglutination pathway.

Due to multiple mechanisms, drug resistance is less likely to develop.

Minimal side effects.

Readily available.

Weaknesses:

Significant lack of research on the bioactive constituents.

There is a lot of irrational fear of this herb.

There are many poor-quality elder prodcts on the market.

 


The Phytochemistry Of Elder

The phytochemical profile of elder is very complex. Despite having nearly 100 "active" ingredients, we can break them down into several categories for easier cataloging.


The berries of elder are a rich source of anthocyanidins (dark blue berries), and anthoxanthins (white berries). 


These chemicals are water soluble flavonoids that are absorbed through the small intestine and reach peak concentration systemically after 30-60 minutes. 


They remain mostly un metabolised before being excreted in the urine. 


These chemicals are antioxidant, and thought to play a role in the inhibition of the M2 ion channels on the surface of influenza A. 


Elder also contains ursolic acid, which has a wide range of medicinal effects including the down regulation of MMp-9 and COX-2 inhibition. These are some of the main anti-inflammatory mechanisms of elder. 


The lignans are considered to be the main active constituents in terms of influenza. 


This is because their unique ability to bind to the viral envelope allows them to interact with and inhibit a wide range of proteins on the viral surface, thus damaging their ability to function. 


It’s not just with influenza, as both elder, and plants with similar ligand constituents like phytolacca have both been shown to inhibit other enveloped viruses including HIV, 

Chemical Profile Of Sambucus (nigra/ebulis).

Chemical class Chemical Name Pharmacology

Flavonoid pigments Anthocyanins (S. nigra/canadensis) and anthoxanthins (S. australasica) Water soluble flavonoids that are absorbed through the small intestine and reach peak concentration systemically after 30-60 minutes. They Remain mostly un metabolised before being excreted in the urine.

Flavonol glycosides quercetin-3-O-rutinoside, kaempferol-3-O-rutinoside and isorhamnetin-3-O-rutinoside (about 90% of the total flavonoid content) Some have been found to bind to viral membranes, possibly delivering main mechanism of actions through hemagglutinin, M2 ion channel, and neuraminidase inhibition.

Phenolic acids 5-O-caVeoylquinic acid and 1,5-di-O-caVeoylquinic acid (about 70% of the total phenolic acid content). Caffeoylquinic acids are mainly found in the plasma and urine as hydroxycinnamate metabolites. Research has suggested that most of the absorption is done in the upper GIT. Peak concentration varies greatly, ranging from 30 min to 6 hours (Tmax).

Triterpenes Ursolic acid Downregulates MMP-9 and inhibits COX-2. Reach peak concentration in the blood after 1 hour. Half life is 4 hours.

Lignans Nigrin b, basic nigrin b, SNA, SNA1, and SNLRP, nigrin f, nigrin s, ebulin 1, ebulin r1, ebulin r2 (type 2 RIPs). ebulitins (Type 1 RIP) RIPs have been shown to bind to viral envelop proteins, and have shown activity on sialic acid in the GIT (not confirmed in the repiratory epithelial tissue). The pharmacokinetics are not well understood.

How To Take Elder For Influenza

Elder comes in everything from liquid extracts, to capsules, to syrups... but which form is best?


 


1. Liquid Extracts

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Elder Extract


Herb Pharm


Made from the berries of Sambucus nigra


Shop Now

Liquid extracts are the preferred form of herbal delivery because they are quickly absorbed into the blood stream, store for long periods of time, and are easy to use. 


Elder liquid extracts can be used to combat influenza within the first 48 hours of infection at a dose of around 2-6 mL/day. 


This form of elder is useful as a prophylactic as well for those who have come in contact with an infected individual. 


Most herbalists, or naturopaths will prepare a combination of elderberry extract with other plant extracts that either enhance the effects of the elder, or ameliorate the side effects. Some popular additions includes ginger, skullcap, and phytolacca. 


 


2. Syrups

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Sambucol® Syrup

Immune*it-Tea


Syrups off an additional benefit to those suffering from influenza. 


The soothing, demulcent activity of the syrup helps to ease a sore throat while simultaneously delivering the active constituents to the upper respiratory tract tissue. 


These are a great method of using elderberry for children and adults alike for its great taste, and additional soothing effects.

. All influenza medications will work only if given within the first 48 hours of infection. 


 


Preventing Side Effects Of Elder

The one thing to be cautious of when taking elder is its main side effect as an emetic. 


This means it is notorious for causing nausea and vomiting. 


The key to avoiding this is to choose an elder product that has been heated first, which allows the RIP 1 lignans to be broken down more efficiently by pepsin in the stomach, thus causing less nauseating effects. 


Secondly, if taking elder and nausea is experienced, it is helpful to simply reduce the dose. The normal dose for elder liquid extract (1:2) is about 2-6 mL/day. Simply reduce the amount taken, or frequency to reduce the nauseating side effects.  


If nausea cannot be avoided when taking elder, or if available, other herbs like ginger can be used to alleviate some of these symptoms. Taking a combination of herbs in this way is both common and recommended. 


 


What Else Is Elder Good For?

 

1. Other Enveloped Viruses

Not only has elder shown beneficial activity towards inhibiting influenza viruses, it has also shown activity towards other enveloped viruses. 


In a study done on a popular elderberry extract known as Sambucol®, it showed non-specific inhibitory activity on a variety of enveloped virus strains including HIV [4]. 


In an In vitro study of the antiviral potential of Sambucus nigra, researchers pretreated infectious bronchitis virus (IBV) (a coronavirus affecting chickens), with a Sambucus nigra extract. 


The enveloped IBV virions treated with Sambucus nigra extract had compromised envelope protein spikes compared to the control by visual inspection [5]. 


This is the same inhibitory mechanism for influenza, and the likely mechanism for its inhibitory effects on a wide range of enveloped viruses.


 

Elder Has Been Shown To Inhibit the Following Enveloped Viruses

Influenza A (various strains

Influenza B

HIV

Feline immunodeficiency virus (FIV)

Herpes simplex virus (HSV)

Tobacco mosaic virus (plant virus)

Mycoviruses (various)

Haemophilus influenzae

Coronavirus (in chickens)

2. Coughs

Sambucus is also considered an antitussive, which means it has the ability to inhibit or reduce the severity of coughing, further adding to the beneficial activity of elder with respiratory infections of influenza. 

Where To Find Elder Extract

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Elder Extract


Other Anti-viral Hrbs


Tea (Camellia Sinensis)


Stevia (Stevia Rebaudiana)


Elder (Sambucus Nigra)


Olive Leaf (Olea Europea)


Reishi (Ganoderma Lucidum)


Gotu Kola (Centella Asiatica)


Bupleurum (Bupleurum Falciform)


Ginger (Zingiber Officinale)


Milk Thistle (Silybum Marianum)


Chinese Skullcap (Scutellaria Baicalensis)

Author:

Justin Cooke


The Sunlight Experiment

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Aug 31, 2017  virology, virus, elder

References:

Nsimba-Lubaki, M., Peumans, W. J., & Allen, A. K. (1986). Isolation and characterization of glycoprotein lectins from the bark of three species of elder, Sambucus ebulus, S. nigra and S. racemosa. Planta, 168(1), 113-118.


Mariotti-Lippi, L.; Bellini, C.; Mori, S. Palaeovegetational reconstruction based on pollen and seeds/fruits from a bronze age archaeological site in Tuscany (Italy). Plant. Biosyst. 2010, 144, 902–908.


Martin, L.; Jacomet, S.; Thiebault, S. Plant economy during the Neolithic in a mountain context: The case of “Le Chenet des Pierres” in the french Alps (Bozel-Savoie, France). Veg. Hist. Archaeobot. 2008, 17, s113–s122.


Konlee, M. (1998). A new triple combination therapy. Positive health news, (17), 12.


Chen, C., Zuckerman, D. M., Brantley, S., Sharpe, M., Childress, K., Hoiczyk, E., & Pendleton, A. R. (2014). Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication. BMC veterinary research, 10(1), 24.

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Why this is the greatest

CBD

rehab

CBD has been shown to help relieve  both chronic pain mental illness, including anxiety, depression, and may help reduce the cravings of alcohol dependency.

Sophisticated consumers know the benefits are amazing

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High-end spas, rehabilitation centers who want to impress clients choose Immune*it-Tea 

Senior Citizens report tremendous improvement in health with regular use

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Artery elasticity, mental clarity, pain reduction, mood elevation.

Trauma Treatment Programs have Incorporated Immune*it-Tea into their client's recovery plans

The ingredients In Immune*it-Tea not only keep patients healthy, but they can help elevate the mood.  For patients undergoing chemotherapy and/or radiation, the ingredients reduce nausea and provide essential vitamins depleted by radiation and chemotherapy. 


For clients who are in recovery from drug and alcohol abuse, or for those who know consuming alcohol may cause damage, but they enjoy indulging anyway --  both the Wild Child Revitalizing Elixir  and the CBD-Infused Wellness brew are known to support and help regenerate (to a certain degree)  liver damage and help support vitality despite a vice or two.


  Much of the harm to the body from drug and alcohol use is caused not from the beer you drink, but the damage is caused by the lack of Thiamine and Magnesium and other essential elements in the body  -- because alcohol and stress can deplete these essential nutrients. 


Even if you only drink a couple of glasses of wine with dinner, it's important to help mitigate some of the potential damage. 


Our Teas are specifically designed for you.  Party Well. Stay Well.


(These statements have not been evaluated by the FDA. This product is not designed to diagnose, treat, cure or prevent any disease.) 

Fitness Coaches & Life Coaches recommend it to their clients

Leading fitness coaches recommend Immune*it-Tea to their clients to keep them strong, particularly while on a 3 day cleanse.  Life Coaches recommend Immune*it-Tea to keep their clients focused, healthy and energized. Those who travel frequently consider it an essential item.

FAQs

Q: is it legal?

A: YES!


Q: Will it get me high?

A: No.  Not at all. CBD is absolutely safe.  It  has none of the side effects of opiates, and has tested as effective as anti-depressants such as Paxil.   In fact, CBD has been shown to counteract the anxiety even in someone is "too high" from marijuana with THC.




Q: How do I know this has genuine CBD -- there are some products that don't have it but make false claims?

A: Our Hemp has been tested by the State of Oregon and has NO pesticides, and tested at a 20% CBD. The Water-Soluable CBD Isolate, which means you absorb 90% more of the effective ingredients has been tested at Pro Verde Lab in Quincy, MA and certified.


Q: Why is this better than "Airborne?" What's the difference?


A: Immune*it-Tea is all natural and has herbs that not only boost the Immune system that protects you from colds and flu, but has herbs known to improve liver function, agents that promote skin and artery health, lower blood pressure and many other ingredients. 

we use water soluble cbd~that means you ABSORB 90% more of the active ingredient with our tea

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Some Information about CBD

And, apart from relief from specific medical conditions, what are the benefits of using cannabidiol (CBD) ?

Anyone interested in improving general health and wellness may enjoy adding CBD into their daily lives.


While research on the cannabinoid is still in its infancy, it is non-toxic and is generally considered to be well-tolerated by a wide variety of individuals.

For the CBD-curious, here are a few smart ways to use CBD oil every day 

(Courtesy of Green Flower):

Microdose supplement

As it turns out, a little CBD can go a long way.

Maybe you've heard about the growing trend of microdosing?

A microdose is a tiny, daily or semi-daily dose. Microdosing CBD is easiest with CBD cannabis oil.

A typical microdose is between 2.5 and 5 milligrams. This dose is often considered too low to be therapeutic for many medical conditions. However, there may be some benefit to microdosing every once in a while.

Rodent research has found that low doses of the cannabinoid reduce pro-inflammatory compounds in the body.

This is a big deal because reduced inflammation can have wide-sweeping beneficial effects on the body, especially during times of stress.

While microdosing may have some immediate benefits just like many vitamin supplements, CBD builds up in the body over time.

Since the cannabinoid is stored in fat, consistent doses of CBD may be able to deliver more meaningful health changes as it accumulates in your system. However, there is no research that suggests what changes this might cause at this particular time.


 Stress relief

Hoping for a quick and easy way to calm down?

Research has shown that doses as low as 2.5, 5, and 10 milligrams of CBD can successfully ease symptoms of anxiety 

Other research suggests that CBD is a neuroprotective antioxidant, potentially protecting the brain from diseases of aging.

As a neuroprotective antioxidant, CBD oil may be particularly good to take after a night of reduced sleep.

The current thinking on the science here is pretty interesting.

Have you ever experienced brain fog after a night of sleep deprivation? There may be a good reason.

During sleep, the brain’s lymphatic system clears out toxins that build up during the day. This is why reduced quality of sleep as you age is thought to be a major contributing factor to neurodegenerative diseases like Alzheimer’s.

CBD treatment is thought to be so powerful that even short-term treatment has been found to improve overall functioning and cognitive performance in mice after suffering ischemic injury. Ischemic injury occurs when the brain is deprived of adequate blood flow, which often happens during a stroke and as a result of heart disease.

Having shot of our CBD Tea is a great way to protect the body from stress-related damage.

Speaking of stress...

Do you know anyone who typically turns to cigarettes or other hard substances when under stress?

Additional research published in 2004 suggests that even low doses of the cannabinoid (5 milligrams) helps prevent habitual, learned behaviors in rodents that were exposed to cocaine and amphetamines.

We are looking further into how to use CBD oil to quit smoking or drinking, etc. You can go ahead and try it out if you want.

Of course, when it comes to holistic stress management, no health single health supplement compares to the long-lasting beneficial effects of healthy diet and lifestyle interventions.

Still, the preclinical research suggests that supplementing with cannabidiol may be an excellent way to give your overall health a meaningful boost. 

It all comes together in an amazing Brew

alcohol aid, health, green tea, vitamins, magnesium, lemon, honey, ginger, elderberries

Wild Child Revitalizing Elixir

We use the finest natural ingredients used in ancient remedies from around the world, and scientific studies by the CDC confirm that these ingredients have anti-inflammatory properties, are high in anti-oxidants, can significantly speed recovery, contribute to heart health and artery elasticity, elevate the mood and may ease join pain, among other benefits.


We blend the finest natural ingredients used for centuries to support liver health, and to boost the immune system. This energizing tea has 84mg of slow-release caffeine, organic honey, elderberry juice, ginger, and a host of top-quality ingredients.  We have fortified it with  minerals and vitamins specifically depleted by alcohol consumption in order to offset SOME of the damage:  Magnesium, selenium, D3, Thiamin and the entire B-complex.  It's great for those who like to party but who want to take care of their bodies, and for travelers who don't want to lug vitamins on trips.  These nutrients are easily absorbed in this great-tasting concentrate.


A note about Magnesium Glycinate: Magnesium is called the “Miracle Mineral” because it is involved in practically every body function.  Unfortunately, it’s also one of the most common nutrient deficiencies today; It is estimated up to 80% of adults are deficient in magnesium because stress, alcohol, processed foods, antibiotics and other common medications quickly deplete this critical mineral, which is why our Wild Child Revitalizing Elixir is a great source of Magnesium.  


We added 20 mg of CBD to the Wild Child Revitalizing Powdered Power Pack, and 10 mg of CBD to each Wild Child Revitalizing Stick Packs

CBD-Inused Wellness Brew

Our top-selling tea. 

Several Purchase Options



Our Customers Love Us!

Our customer base has expanded so much, initially through word-of-mouth recommendations! 

FAQs

Q:  This tea is pricey -- is it worth it?

A:  WE don't cut corners -- we use the very best Ceylon Cinnamon oil, Real Vanilla, (nothing imitation).  We just met with a Hawaiian Vanilla Farmer on the slopes of Mauna Kea to provide the Organic Vanilla  for this tea.  We use the most bio-available form of vitamins.  If you use this tea regularly, you will function at your best.  How much does it cost you if you miss work, miss a vacation, miss an opportunity?  Drinking this regularly can help protect your health.

This really works

Science-Based Evidence on the effectiveness of our products

 

Featured Articles in Internal Medicine

IN THE NEWS

Researchers find a new treatment for the common cold

John Murphy, MDLinx | January 25, 2019

For cold and flu-like symptoms, most consumers take over-the-counter medicines, while clinicians can prescribe antiviral drugs such as Tamiflu. But none of these is a silver bullet against the common cold or flu. Now, researchers have shown that elderberry syrup—a remedy as old as folklore—substantially reduces both symptom severity and symptom duration for colds and flu.

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elderberry syrup

The new cure for the common cold has an old tradition.

“Supplementation with a standardized elderberry extract is significantly effective at reducing the total duration and severity of upper respiratory symptoms, as compared to a placebo group,” wrote the researchers, led by Jessie Hawkins, PhD, Research Director, Franklin Institute of Wellness, Franklin, TN, in a recent meta-analysis in Complementary Therapies in Medicine.

The authors added, “These findings present an alternative to antibiotic misuse for upper respiratory symptoms due to viral infections, and a potentially safer alternative to prescription drugs for routine cases of the common cold and influenza.”

Old medicine, modern times

Elderberry syrup has been used as a cold remedy for a long, long time. Hans Christian Anderson even wrote a fairy tale about a boy with a cold who drank hot tea made from elder blossoms. But only in the past few years have researchers taken a scientific look at whether this folk medicine actually does treat colds and flu.

Researchers performing in vitro studies have found that elderberry extract is active against human pathogenic bacteria as well as influenza viruses (H1N1). In separate clinical trials in humans, investigators demonstrated that liquid elderberry extract and elderberry extract lozenges each reduced the severity and duration of cold and flu-like symptoms.

Despite these investigations, no large-scale studies or meta-analyses have examined elderberry extract’s effects on colds and flu. To that end, Dr. Hawkins and coauthors undertook the first meta-analysis to study elderberry supplementation and upper respiratory symptoms. Their literature search uncovered 137 articles, only four of which met their strict criteria. This resulted in a total of 180 participants—89 in the elderberry group and 91 in the control group.

SEE ALSO: When will scientists cure the common cold?

Because the four studies were heterogeneous, the researchers were able to apply a random effects model to evaluate the effect of elderberry supplementation on upper respiratory symptoms. Calculations yielded a large mean effect size of 1.717, which indicated that elderberry supplementation substantially reduces the duration of upper respiratory symptoms.

Getting the flu vaccine didn’t significantly alter the effects of elderberry supplementation, the researchers also noted. In addition, they found that elderberry supplementation reduced symptoms of both colds and flu, but the effect was greater for flu symptoms than for cold symptoms.

A household staple

“These findings are exciting,” Dr. Hawkins said. “While elderberry syrup has become a household staple, studies on its effects have been small and are sparse. We are now able to quantify the effects of elderberry and to understand how these effects differ based on factors such as underlying pathology and vaccination status.”

The researchers acknowledged limitations to their meta-analysis, noting that the number of randomized controlled studies was small and represented only 180 total patients. Also, three of the four studies included were funded by elderberry supplement manufacturing companies, and the fourth study didn’t name its funding source.

SEE ALSO: NIAID researchers discover rare genetic susceptibility to common cold

Lastly, while elderberry extract may not be a staple in every household, despite what Dr. Hawkins says, it is commonly available in most drug stores and online retailers in the form of syrup, lozenges and gummies. Elderberry syrup can also be made at home, but it must be thoroughly heated to remove toxic compounds in the berries that could otherwise cause severe stomach upset, the authors advised.

This study was supported by the Franklin Institute of Wellness research department.

Related Links:

Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials 

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